Ozempic and Wegovy: Weight-Loss Drugs That Might Slow Down Aging
Recently, groundbreaking research has suggested that weight-loss drugs like Ozempic and Wegovy, which contain the active ingredient semaglutide, could do more than just help with weight management. According to a new study presented at the European Society of Cardiology Conference in London, these medications might actually play a role in slowing down the aging process and extending lifespan.
The study focused on semaglutide’s effects on people who are overweight or obese and have cardiovascular disease. While it was initially believed that these drugs primarily reduced the risk of cardiovascular events, new findings reveal a broader range of benefits. Researchers discovered that individuals taking semaglutide had lower overall mortality rates, not just reduced cardiovascular deaths. This includes a significant decrease in deaths from infections, which was an unexpected and promising outcome.
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Prof. Harlan Krumholz from Yale School of Medicine highlighted the surprising nature of these results, noting that semaglutide's benefits extend beyond cardiovascular health. “It’s not just avoiding heart attacks. These are health promoters. It wouldn’t surprise me if improving people’s health this way actually slows down the aging process,” he said.
The study involved 17,604 participants aged 45 or older with cardiovascular disease but no diabetes. Over a period of more than three years, half of the participants received semaglutide while the other half were given a placebo. The results showed that those on semaglutide had a notably lower risk of dying from various causes, including infections, compared to those on the placebo.
The research team, led by Harvard’s Benjamin Scirica, was particularly surprised by the robust reduction in non-cardiovascular deaths. “These findings reinforce that overweight and obesity increase the risk of death from multiple causes, which can be mitigated with therapies like semaglutide,” Scirica explained.
This new perspective on semaglutide’s benefits suggests that weight-loss drugs could play a crucial role in enhancing overall health and longevity, potentially offering more than just a solution to weight-related issues. As scientists continue to explore these findings, it is becoming increasingly clear that these medications might be key players in future healthcare strategies aimed at improving quality of life and extending healthy lifespan.
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