Prisco’s Bold NFL Week 1 Predictions
Week 1 of the NFL season is always a mix of excitement, nerves, and plenty of bold predictions. Pete Prisco from CBS Sports has laid out his picks for the opening week, and as always, they’ve sparked some buzz. Last year, he admitted, his predictions weren’t the sharpest—but with a clean slate and fresh optimism, he’s ready to turn it around. Let’s walk through his calls for the biggest matchups.
The season kicks off Thursday night with a heavyweight battle: the defending champion Philadelphia Eagles hosting the Dallas Cowboys. Despite the drama of Dallas moving Micah Parsons, Prisco sees Dak Prescott keeping it close but predicts the Eagles edge it out, 27–24. On Friday, fans get a rare international matchup in Brazil as the Chiefs take on the Chargers. Patrick Mahomes, now protected by a retooled offensive line, is expected to shine. With the Chargers missing key tackle Rashawn Slater, Kansas City is picked to roll, 30–21.
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Sunday brings a full slate. The Buccaneers and Falcons clash in an NFC South showdown, and Prisco is leaning toward Baker Mayfield leading Tampa Bay to a 28–24 win. Up in Ohio, Joe Burrow is expected to outduel Joe Flacco, with Cincinnati taking a narrow 30–27 victory over Cleveland. Meanwhile, Daniel Jones makes his debut as quarterback for the Colts against Miami. In what could be a shootout, Prisco has Indianapolis sneaking by, 33–30.
The Jets and Steelers matchup has its own drama—Aaron Rodgers facing his old team while Justin Fields battles his former squad. Prisco likes the Jets in a defensive struggle, 20–16. Across the division, Russell Wilson makes his Giants debut against Washington, but Jayden Daniels is seen holding on for a 26–23 Commanders win.
In the late afternoon games, rookies and veterans collide. Cameron Ward’s first start for Tennessee comes against Denver’s suffocating defense, and Prisco thinks the Broncos win comfortably, 26–13. The 49ers, bolstered by Christian McCaffrey and Trent Williams, are picked to handle Seattle 23–17, even in the loudest stadium in football. And over in Green Bay, the Lions-Packers showdown looks like a shootout. Prisco gives the edge to Jordan Love and newly acquired Micah Parsons, 35–30.
Sunday night’s prime-time game is a blockbuster: the Ravens traveling to Buffalo. Lamar Jackson will be chasing revenge after last year’s playoff loss, but Josh Allen and the Bills are predicted to hold strong, 34–31. Finally, Monday night closes Week 1 with a rookie debut—J.J. McCarthy for the Vikings. Unfortunately for Minnesota, Chicago’s Caleb Williams and new coach Ben Johnson are picked to spoil it, 27–21.
From upset alerts to rookie debuts, Prisco’s predictions set the tone for what could be an unpredictable season. Week 1 always brings surprises, but if his forecast holds, we’ll be looking at a mix of close thrillers, statement wins, and a whole lot of drama right out of the gate.
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